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Roles of Cbln1 in Non-Motor Functions of Mice.
Otsuka S, Konno K, Abe M, Motohashi J, Kohda K, Sakimura K, Watanabe M, Yuzaki M. Otsuka S, et al. J Neurosci. 2016 Nov 16;36(46):11801-11816. doi: 10.1523/JNEUROSCI.0322-16.2016. J Neurosci. 2016. PMID: 27852787 Free PMC article.
Although genes encoding Cbln1 and its postsynaptic receptor, the delta2 glutamate receptor (GluD2), are suggested to be associated with autistic-like traits and many psychiatric disorders, whether such cognitive impairments are caused by cerebellar dysfunction remai …
Although genes encoding Cbln1 and its postsynaptic receptor, the delta2 glutamate receptor (GluD2), are suggested to be associated wi …
Multiomic Analyses of Dopaminergic Neurons Isolated from Human Substantia Nigra in Parkinson's Disease: A Descriptive and Exploratory Study.
Zaccaria A, Antinori P, Licker V, Kövari E, Lobrinus JA, Burkhard PR. Zaccaria A, et al. Cell Mol Neurobiol. 2022 Nov;42(8):2805-2818. doi: 10.1007/s10571-021-01146-8. Epub 2021 Sep 15. Cell Mol Neurobiol. 2022. PMID: 34528139 Free PMC article.
This multiomic analysis highlighted differential expression of 52 genes and 33 proteins, including molecules of interest already known to be dysregulated in PD, such as LRP2, PNMT, CXCR4, MAOA and CBLN1 genes, or the Aldehyde dehydrogenase 1 protein. On the other hand, des …
This multiomic analysis highlighted differential expression of 52 genes and 33 proteins, including molecules of interest already known to be …
Is the loss of thalamostriatal neurons protective in parkinsonism?
Kusnoor SV, Muly EC, Morgan JI, Deutch AY. Kusnoor SV, et al. Parkinsonism Relat Disord. 2009 Dec;15 Suppl 3(Suppl 3):S162-6. doi: 10.1016/S1353-8020(09)70806-5. Parkinsonism Relat Disord. 2009. PMID: 20082981 Free PMC article.
We discuss the possible transsynaptic determination of CM-PF loss secondary to nigrostriatal dopamine degeneration, and suggest that expression of the glycoprotein cerebellin1 (Cbln1) in CM-PF neurons may play an important role in striatal synaptic remodeling in parkinsoni …
We discuss the possible transsynaptic determination of CM-PF loss secondary to nigrostriatal dopamine degeneration, and suggest that express …